Uveitis is inflammation of the eye. It is a common Extraintestinal Manifestation of Crohn's Disease.

Certain gene mutations in Crohn's Disease - associated disease are correlated with Uveitis. For example, the Nod2 / Card15 Gene mutation increases the risk of uveitis.



  • Redness of the eye
  • Blurred vision
  • Sensitivity to light (photophobia)
  • Dark, floating spots along the visual field
  • Eye pain

Potential Complications

The outlook for Uveitis is good with treatment. Failure to receive or follow treatment may lead to:
  • Retinal edema
  • Glaucoma
  • Band keratopathy
  • Cataracts
  • Permanent vision loss


Alternative Treatments

Animal studies have shown supplementation of Vitamin B1 and Vitamin E improved Uveitis.[1][2] As Vitamin E is a fat soluble vitamin, many people with Crohn's Disease will potentially be deficient. As many people with Crohn's Disease are deficient in Vitamin B12 and Folate (Vitamin B9) and supplement just those B vitamins, according to the University of Maryland Medical Center, that can lead to imbalances in other B Vitamins which may lead to a B1 deficiency. If attempting B vitamin supplementation, be sure to take a Complex B vitamin that includes each of the B vitamins.


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