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Vitamin B2 - Riboflavin


Vitamin B2 / Riboflavin

Vitamin B2 (Riboflavin) is a water soluble vitamin. Riboflavin deficiency alters iron metabolism. Riboflavin deficiency may impair iron absorption, increase intestinal loss of iron, and/or reduce iron utilization for the creation of hemoglobin. Improving riboflavin levels has been found to increase circulating hemoglobin levels. Correction of riboflavin deficiency in individuals who are both riboflavin and iron deficient improves the response of iron-deficiency anemia to iron therapy.[2]. Riboflavin deficiency is known as Ariboflavinosis and is endemic is certain areas of the world and in specific populations such as vegans.[3]

Symptoms of Vitamin B2 Deficiency

Greasy/red scaly skin on face and sides of nose, sore/burning/red/inflamed tongue, peeling lips, split / cracked lips with sores (cheliosis), sores at the corners of the mouth (angular stomatitis), sensitivity to sunlight, inflammation of the tongue, seborrheic dermatitis or pseudo-syphilis (particularly affecting the scrotum or labia majora and the mouth), pharyngitis (sore throat), vascularization of the cornea (red eyes), decreased red blood cell count (normochromic normocytic anemia), hyperemia (increase blood flow to areas of the body), preeclampsia in pregnant women, and edema of the pharyngeal and oral mucosa.

Anatomy of Absorption

It appears that vitamin B2 is absorbed in both the small and large intestine[1] though other sources state the proximal small intestine and is catalyzed by enterocytes.[goto=62a][62] There is evidence that the current RDA is too low or thresholds for deficiency are incorrect.3

Recommended Daily Intake

Natural Sources of Vitamin B2:


No toxic or adverse effects of high riboflavin intake in humans are known.[2]

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